PhD project:

A successful applicant will investigate druggable cell-intrinsic mechanisms in modulating an immune cell response in pancreatic cancer. The applicant will employ complex 3D co-culture model systems, genetically engineered mouse models as well as human organoid models to perform shRNA and CRISPR library-based screening approaches and study biochemical and biophysical aspects of tumor-niche interactions for entering clinical translation.

What we offer:

• Potential for meaningful research and high-impact publications 
• Opportunity for further projects to guarantee a successful PhD
• A strong base for a successful (scientific) career
• National and international collaborations
• Multifarious work including sophisticated 3D co-culture model system and patient-derived organoid models
• Excellent technical support and well-established methods
• Tight supervision, while allowing autonomy and giving responsibility
• Young and dedicated team with familial team-spirit
• Flat hierarchies

A successful candidate will be closely supervised by Dr. Yuanna Lin.
PD Dr. Lin is a Clinician Scientist and junior group leader. She has previously worked at the University Hospital Hamburg-Eppendorf and was a postdoc at Georgetown University in Washington DC. 

What we expect: 

• Very high intrinsic motivation and dedication to the project
• Collaborative, proactive, and ambitious spirit
• Structuredness and reliability
• Excellent M.Sc. in Life Sciences, Bioinformatics or related discipline