The Department of Pediatrics and Adolescent Medicine at Ulm University Medical Center (Head: Prof. Dr. Miriam Erlacher) is searching immediately for a
PhD Position (f/m/d)
to investigate the molecular mechanisms of UBTF-TD in myeloid malignancies
to investigate the molecular mechanisms of UBTF-TD in myeloid malignancies
The University Hospital Ulm and its employees stand for a modern and high quality patient care, excellent university research and medical education focused on the future as well as apprenticeships in attractive professional fields. The requirements for this are qualified and committed employees.
The laboratory is embedded within the Children’s Hospital at Ulm University Medical Center. The department is equipped with state-of-the-art technologies, including cell sorters, flow cytometers, and access to various core facilities, and fosters close collaboration across research groups. We are a young, multidisciplinary, and international team investigating hematopoiesis, bone marrow failure, and leukemogenesis through a range of related projects.
In this project, we investigate how UBTF tandem duplications (UBTF-TD) drive therapy resistance and leukemic transformation in MDS and AML. Using engineered cell models and patient samples from the EWOG-MDS registry hosted by our department, we will study their impact on ribosome biogenesis, transcriptional programs, and hematopoietic function. The position provides training in molecular and translational leukemia research. The candidate is expected to work independently, contribute to student supervision, and help shape future research directions.
We Offer:
Your Profile:
In this project, we investigate how UBTF tandem duplications (UBTF-TD) drive therapy resistance and leukemic transformation in MDS and AML. Using engineered cell models and patient samples from the EWOG-MDS registry hosted by our department, we will study their impact on ribosome biogenesis, transcriptional programs, and hematopoietic function. The position provides training in molecular and translational leukemia research. The candidate is expected to work independently, contribute to student supervision, and help shape future research directions.
We Offer:
- Above-average compensation according to the collective bargaining agreement of the state of Baden-Württemberg
- Annual bonus and company pension scheme
- Individualized on-the-job training
- Opportunities for personal and professional development
- Work-life balance initiatives, e.g., on-site company kindergarten and nursery
- Public transport subsidy
- Company health promotion programs (e.g., partnerships with various fitness studios)
- A wide range of corporate benefits/discounts
Your Profile:
- the candidate should have an excellent master’s degree in the field of molecular medicine/biochemistry/immunology/bioinformatics or related disciplines
- Strong bioinformatics expertise, including proficiency in R and Python for genomic data analysis, transcriptomics, and statistical modeling
- FELASA approved training would be an asset
- we expect exceptional interest in conducting in vivo scientific research
- good speaking and writing skills in English and German are required
- B2 driving license would be an asset
Contract: limited
Level of employment: part-time
application deadline: 31.05.2026
